ctcRbase

Entry Detail

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General Information

Database ID: PRAD03266 Cancer Type: prostate cancer Dataset: GSE104209 CTCs/CTM Isolation Method: CTC-iChip

Gene Information

ncRNA Symbol: SERPINI1 Full Name: serpin family I member 1 Category: mRNA Synonyms: PI12|neuroserpin Chromosome: chr3 Strand: + Coordinate: Start Site(bp): 167735243 End Site(bp): 167825568 Gene Summary: This gene encodes a member of the serpin superfamily of serine proteinase inhibitors. The protein is primarily secreted by axons in the brain, and preferentially reacts with and inhibits tissue-type plasminogen activator. It is thought to play a role in the regulation of axonal growth and the development of synaptic plasticity. Mutations in this gene result in familial encephalopathy with neuroserpin inclusion bodies (FENIB), which is a dominantly inherited form of familial encephalopathy and epilepsy characterized by the accumulation of mutant neuroserpin polymers. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000163536 HGNC ID: HGNC:8943 Entrez Gene: 5274

Expression Profile of SERPINI1 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-181a-5p YES YES NO hsa-miR-181b-5p YES YES NO hsa-miR-181c-5p YES YES NO hsa-miR-181d-5p YES YES NO hsa-miR-200b-3p YES YES YES hsa-miR-200c-3p YES YES YES hsa-miR-21-5p YES YES NO hsa-miR-218-5p YES YES YES hsa-miR-374a-5p YES YES NO hsa-miR-374b-5p YES YES NO hsa-miR-429 YES YES YES hsa-miR-455-5p YES YES NO hsa-miR-543 YES YES YES hsa-miR-590-5p YES YES NO Display: