Entry Detail



General Information

Database ID:BRCA00030
Cancer Type:breast cancer
Dataset:GSE41245
CTCs/CTM Isolation Method:CTC-Chip



Gene Information

ncRNA Symbol:HBB
Full Name:hemoglobin subunit beta
Category:mRNA
Synonyms:CD113t-C|ECYT6|beta-globin
Chromosome:chr11
Strand:-
Coordinate:
Start Site(bp):5225464End Site(bp):5229395
Gene Summary:The alpha (HBA) and beta (HBB) loci determine the structure of the 2 types of polypeptide chains in adult hemoglobin, Hb A. The normal adult hemoglobin tetramer consists of two alpha chains and two beta chains. Mutant beta globin causes sickle cell anemia. Absence of beta chain causes beta-zero-thalassemia. Reduced amounts of detectable beta globin causes beta-plus-thalassemia. The order of the genes in the beta-globin cluster is 5'-epsilon -- gamma-G -- gamma-A -- delta -- beta--3'. [provided by RefSeq, Jul 2008]
External Links:
Ensembl ID:ENSG00000244734
HGNC ID:HGNC:4827
Entrez Gene:3043



Expression Profile of HBB Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:NA
Display:N/A