Entry Detail



General Information

Database ID:BRCA00085
Cancer Type:breast cancer
Dataset:GSE111065
CTCs/CTM Isolation Method:microfluidics immunofluorescence



Gene Information

ncRNA Symbol:ACTB
Full Name:actin beta
Category:mRNA
Synonyms:BRWS1|PS1TP5BP1
Chromosome:chr7
Strand:-
Coordinate:
Start Site(bp):5527151End Site(bp):5563784
Gene Summary:This gene encodes one of six different actin proteins. Actins are highly conserved proteins that are involved in cell motility, structure, integrity, and intercellular signaling. The encoded protein is a major constituent of the contractile apparatus and one of the two nonmuscle cytoskeletal actins that are ubiquitously expressed. Mutations in this gene cause Baraitser-Winter syndrome 1, which is characterized by intellectual disability with a distinctive facial appearance in human patients. Numerous pseudogenes of this gene have been identified throughout the human genome. [provided by RefSeq, Aug 2017]
External Links:
Ensembl ID:ENSG00000075624
HGNC ID:HGNC:132
Entrez Gene:60



Expression Profile of ACTB Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-miR-1-3p
YES
YES
YES
hsa-miR-145-5p
YES
YES
YES
hsa-miR-19a-3p
YES
YES
NO
hsa-miR-19b-3p
YES
YES
NO
hsa-miR-205-5p
YES
YES
YES
hsa-miR-206
YES
YES
YES
hsa-miR-216a-5p
YES
YES
NO
hsa-miR-33a-5p
YES
YES
NO
hsa-miR-33b-5p
YES
YES
NO
hsa-miR-495-3p
YES
YES
NO
hsa-miR-548o-3p
YES
NO
NO
hsa-miR-613
YES
YES
YES
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