ctcRbase

Entry Detail

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General Information

Database ID: BRCA00393 Cancer Type: breast cancer Dataset: GSE41245 CTCs/CTM Isolation Method: CTC-Chip

Gene Information

ncRNA Symbol: PDGFA Full Name: platelet derived growth factor subunit A Category: mRNA Synonyms: PDGF-A|PDGF1 Chromosome: chr7 Strand: - Coordinate: Start Site(bp): 497258 End Site(bp): 520296 Gene Summary: This gene encodes a member of the protein family comprised of both platelet-derived growth factors (PDGF) and vascular endothelial growth factors (VEGF). The encoded preproprotein is proteolytically processed to generate platelet-derived growth factor subunit A, which can homodimerize, or alternatively, heterodimerize with the related platelet-derived growth factor subunit B. These proteins bind and activate PDGF receptor tyrosine kinases, which play a role in a wide range of developmental processes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015] External Links: Ensembl ID: ENSG00000197461 HGNC ID: HGNC:8799 Entrez Gene: 5154

Expression Profile of PDGFA Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-135a-5p YES YES YES hsa-miR-135b-5p YES YES YES hsa-miR-1-3p YES YES YES hsa-miR-153-3p YES YES YES hsa-miR-186-5p YES YES YES hsa-miR-194-5p YES NO YES hsa-miR-196a-5p YES YES NO hsa-miR-196b-5p YES YES NO hsa-miR-206 YES YES YES hsa-miR-221-3p YES NO YES hsa-miR-222-3p YES NO YES hsa-miR-23a-3p YES YES YES hsa-miR-23b-3p YES YES YES hsa-miR-320a YES YES NO hsa-miR-320b YES YES NO hsa-miR-320c YES YES NO hsa-miR-320d YES YES NO hsa-miR-329-3p YES NO NO hsa-miR-335-5p YES YES NO hsa-miR-362-3p YES NO NO hsa-miR-375 YES NO YES hsa-miR-376c-3p YES NO YES hsa-miR-448 YES YES NO hsa-miR-494-3p YES YES YES hsa-miR-495-3p YES YES NO hsa-miR-613 YES YES YES hsa-miR-655-3p YES NO YES hsa-miR-873-5p YES NO YES Display: