| ncRNA Symbol: | SPINT2 | | Full Name: | serine peptidase inhibitor, Kunitz type 2 | | Category: | mRNA | | Synonyms: | DIAR3|HAI-2|HAI2|Kop|PB | | Chromosome: | chr19 | | Strand: | + | | Coordinate: | | Start Site(bp): | 38244035 | End Site(bp): | 38292614 |
| | Gene Summary: | This gene encodes a transmembrane protein with two extracellular Kunitz domains that inhibits a variety of serine proteases. The protein inhibits HGF activator which prevents the formation of active hepatocyte growth factor. This gene is a putative tumor suppressor, and mutations in this gene result in congenital sodium diarrhea. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009] | | External Links: | |
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