| ncRNA Symbol: | ITGA2B |
| Full Name: | integrin subunit alpha 2b |
| Category: | mRNA |
| Synonyms: | BDPLT16|BDPLT2|CD41|CD41B|GP2B|GPIIb|GT|GTA|HPA3|PPP1R93 |
| Chromosome: | chr17 |
| Strand: | - |
| Coordinate: | | Start Site(bp): | 44372180 | End Site(bp): | 44389505 |
|
| Gene Summary: | This gene encodes a member of the integrin alpha chain family of proteins. The encoded preproprotein is proteolytically processed to generate light and heavy chains that associate through disulfide linkages to form a subunit of the alpha-IIb/beta-3 integrin cell adhesion receptor. This receptor plays a crucial role in the blood coagulation system, by mediating platelet aggregation. Mutations in this gene are associated with platelet-type bleeding disorders, which are characterized by a failure of platelet aggregation, including Glanzmann thrombasthenia. [provided by RefSeq, Jan 2016] |
| External Links: | |