ctcRbase

Entry Detail

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General Information

Database ID: BRCA00836 Cancer Type: breast cancer Dataset: GSE67939 CTCs/CTM Isolation Method: Cluster-Chip

Gene Information

ncRNA Symbol: SRGN Full Name: serglycin Category: mRNA Synonyms: PPG|PRG|PRG1 Chromosome: chr10 Strand: + Coordinate: Start Site(bp): 69088106 End Site(bp): 69104811 Gene Summary: This gene encodes a protein best known as a hematopoietic cell granule proteoglycan. Proteoglycans stored in the secretory granules of many hematopoietic cells also contain a protease-resistant peptide core, which may be important for neutralizing hydrolytic enzymes. This encoded protein was found to be associated with the macromolecular complex of granzymes and perforin, which may serve as a mediator of granule-mediated apoptosis. Two transcript variants, only one of them protein-coding, have been found for this gene. [provided by RefSeq, Jul 2010] External Links: Ensembl ID: ENSG00000122862 HGNC ID: HGNC:9361 Entrez Gene: 5552

Expression Profile of SRGN Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-let-7a-5p YES YES NO hsa-let-7b-5p YES YES NO hsa-let-7c-5p YES YES NO hsa-let-7d-5p YES YES NO hsa-let-7e-5p YES YES NO hsa-let-7f-5p YES YES NO hsa-let-7g-5p YES YES NO hsa-miR-10a-5p YES YES NO hsa-miR-10b-5p YES YES NO hsa-miR-129-5p YES YES NO hsa-miR-181a-5p YES YES NO hsa-miR-181b-5p YES YES NO hsa-miR-181c-5p YES YES NO hsa-miR-181d-5p YES YES NO hsa-miR-194-5p YES YES NO hsa-miR-340-5p YES YES NO hsa-miR-410-3p YES YES NO hsa-miR-433-3p YES YES NO hsa-miR-543 YES YES NO hsa-miR-873-5p YES YES NO hsa-miR-9-5p YES YES NO Display: