ctcRbase

Entry Detail

---



General Information

Database ID: BRCA00974 Cancer Type: breast cancer Dataset: GSE41245 CTCs/CTM Isolation Method: CTC-Chip

Gene Information

ncRNA Symbol: DNMT3A Full Name: DNA methyltransferase 3 alpha Category: mRNA Synonyms: DNMT3A2|M.HsaIIIA|TBRS Chromosome: chr2 Strand: - Coordinate: Start Site(bp): 25227855 End Site(bp): 25342590 Gene Summary: CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase that is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes to the cytoplasm and nucleus and its expression is developmentally regulated. [provided by RefSeq, Mar 2016] External Links: Ensembl ID: ENSG00000119772 HGNC ID: HGNC:2978 Entrez Gene: 1788

Expression Profile of DNMT3A Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-101-3p YES YES YES hsa-miR-129-5p YES YES YES hsa-miR-132-3p YES YES YES hsa-miR-136-5p YES NO YES hsa-miR-137 YES NO YES hsa-miR-143-3p YES YES YES hsa-miR-144-3p YES YES NO hsa-miR-150-5p YES YES NO hsa-miR-194-5p YES YES YES hsa-miR-199a-3p YES NO YES hsa-miR-199b-3p YES NO YES hsa-miR-200b-3p YES YES YES hsa-miR-200c-3p YES YES YES hsa-miR-204-5p YES YES NO hsa-miR-211-5p YES YES NO hsa-miR-212-3p YES YES YES hsa-miR-218-5p YES NO YES hsa-miR-25-3p YES NO YES hsa-miR-27a-3p YES YES NO hsa-miR-27b-3p YES YES NO hsa-miR-29a-3p YES YES YES hsa-miR-29b-3p YES YES YES hsa-miR-29c-3p YES YES YES hsa-miR-30a-5p YES YES YES hsa-miR-30b-5p YES YES YES hsa-miR-30c-5p YES YES YES hsa-miR-30d-5p YES YES YES hsa-miR-30e-5p YES YES YES hsa-miR-32-5p YES NO YES hsa-miR-335-5p YES YES NO hsa-miR-340-5p YES YES NO hsa-miR-363-3p YES NO YES hsa-miR-367-3p YES NO YES hsa-miR-410-3p YES YES YES hsa-miR-429 YES YES YES hsa-miR-487a-3p YES NO YES hsa-miR-488-3p YES YES NO hsa-miR-495-3p YES YES YES hsa-miR-543 YES YES NO hsa-miR-92a-3p YES NO YES hsa-miR-92b-3p YES NO YES Display: