ctcRbase

Entry Detail

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General Information

Database ID: BRCA01079 Cancer Type: breast cancer Dataset: GSE86978 CTCs/CTM Isolation Method: CTC-iChip

Gene Information

ncRNA Symbol: AP2M1 Full Name: adaptor related protein complex 2 subunit mu 1 Category: mRNA Synonyms: AP50|CLAPM1|mu2 Chromosome: chr3 Strand: + Coordinate: Start Site(bp): 184174689 End Site(bp): 184184091 Gene Summary: This gene encodes a subunit of the heterotetrameric coat assembly protein complex 2 (AP2), which belongs to the adaptor complexes medium subunits family. The encoded protein is required for the activity of a vacuolar ATPase, which is responsible for proton pumping occurring in the acidification of endosomes and lysosomes. The encoded protein may also play an important role in regulating the intracellular trafficking and function of CTLA-4 protein. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2015] External Links: Ensembl ID: ENSG00000161203 HGNC ID: HGNC:564 Entrez Gene: 1173

Expression Profile of AP2M1 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-133a-3p YES NO YES hsa-miR-133b YES NO YES hsa-miR-138-5p YES YES NO hsa-miR-139-5p YES YES NO hsa-miR-193a-3p YES YES YES hsa-miR-193b-3p YES YES YES hsa-miR-19a-3p YES YES NO hsa-miR-19b-3p YES YES NO hsa-miR-218-5p YES YES NO hsa-miR-224-5p YES YES YES hsa-miR-330-3p YES NO YES hsa-miR-342-3p YES YES YES hsa-miR-377-3p YES YES NO hsa-miR-378a-3p YES YES NO hsa-miR-422a YES YES NO hsa-miR-423-5p YES NO YES hsa-miR-9-5p YES YES YES Display: