Entry Detail



General Information

Database ID:BRCA01089
Cancer Type:breast cancer
Dataset:GSE55807
CTCs/CTM Isolation Method:CTC-iChip



Gene Information

ncRNA Symbol:BANF1
Full Name:barrier to autointegration factor 1
Category:mRNA
Synonyms:BAF|BCRP1|D14S1460|NGPS
Chromosome:chr11
Strand:+
Coordinate:
Start Site(bp):66002079End Site(bp):66004149
Gene Summary:The protein encoded by this gene was first identified by its ability to protect retroviruses from intramolecular integration and therefore promote intermolecular integration into the host cell genome. The protein forms a homodimer which localizes to both the nucleus and cytoplasm and is specifically associated with chromosomes during mitosis. This protein binds to double stranded DNA in a non-specific manner and also binds to LEM-domain containing proteins of the nuclear envelope. This protein is thought to facilitate nuclear reassembly by binding with both DNA and inner nuclear membrane proteins and thereby recruit chromatin to the nuclear periphery. Alternative splicing results in multiple transcript variants encoding the same protein.[provided by RefSeq, Jan 2009]
External Links:
Ensembl ID:ENSG00000175334
HGNC ID:HGNC:17397
Entrez Gene:8815



Expression Profile of BANF1 Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-miR-134-5p
YES
YES
NO
hsa-miR-150-5p
YES
YES
NO
hsa-miR-28-5p
YES
YES
NO
hsa-miR-320a
YES
YES
NO
hsa-miR-320b
YES
YES
NO
hsa-miR-320c
YES
YES
NO
hsa-miR-320d
YES
YES
NO
hsa-miR-335-5p
YES
YES
NO
hsa-miR-382-5p
YES
YES
NO
hsa-miR-708-5p
YES
YES
NO
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