ctcRbase

Entry Detail

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General Information

Database ID: BRCA01111 Cancer Type: breast cancer Dataset: GSE75367 CTCs/CTM Isolation Method: micromanipulation immunofluorescence

Gene Information

ncRNA Symbol: SNCA Full Name: synuclein alpha Category: mRNA Synonyms: NACP|PARK1|PARK4|PD1 Chromosome: chr4 Strand: - Coordinate: Start Site(bp): 89724099 End Site(bp): 89838315 Gene Summary: Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Alternatively spliced transcripts encoding different isoforms have been identified for this gene. [provided by RefSeq, Feb 2016] External Links: Ensembl ID: ENSG00000145335 HGNC ID: HGNC:11138 Entrez Gene: 6622

Expression Profile of SNCA Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-144-3p YES YES NO hsa-miR-148a-3p YES YES NO hsa-miR-148b-3p YES YES NO hsa-miR-152-3p YES YES NO hsa-miR-153-3p YES YES YES hsa-miR-374a-5p YES YES NO hsa-miR-374b-5p YES YES NO hsa-miR-487b-3p YES YES NO hsa-miR-488-3p YES YES NO hsa-miR-495-3p YES YES NO hsa-miR-7-5p YES YES YES Display: