ctcRbase

Entry Detail

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General Information

Database ID: BRCA01380 Cancer Type: breast cancer Dataset: GSE41245 CTCs/CTM Isolation Method: CTC-Chip

Gene Information

ncRNA Symbol: GTF2I Full Name: general transcription factor IIi Category: mRNA Synonyms: BAP135|BTKAP1|DIWS|GTFII-I|IB291|SPIN|TFII-I|WBS|WBSCR6 Chromosome: chr7 Strand: + Coordinate: Start Site(bp): 74657667 End Site(bp): 74760692 Gene Summary: This gene encodes a phosphoprotein containing six characteristic repeat motifs. The encoded protein binds to the initiator element (Inr) and E-box element in promoters and functions as a regulator of transcription. This locus, along with several other neighboring genes, is deleted in Williams-Beuren syndrome. There are many closely related genes and pseudogenes for this gene on chromosome 7. This gene also has pseudogenes on chromosomes 9, 13, and 21. Alternatively spliced transcript variants encoding multiple isoforms have been observed. [provided by RefSeq, Jul 2013] External Links: Ensembl ID: ENSG00000263001 HGNC ID: HGNC:4659 Entrez Gene: 2969

Expression Profile of GTF2I Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-let-7a-5p YES YES YES hsa-let-7b-5p YES YES YES hsa-let-7c-5p YES YES YES hsa-let-7d-5p YES YES YES hsa-let-7e-5p YES YES YES hsa-let-7f-5p YES YES YES hsa-let-7g-5p YES YES YES hsa-let-7i-5p YES YES YES hsa-miR-136-5p YES YES YES hsa-miR-186-5p YES YES NO hsa-miR-194-5p YES YES NO hsa-miR-21-5p YES YES NO hsa-miR-216a-5p YES YES NO hsa-miR-27a-3p YES YES YES hsa-miR-27b-3p YES YES YES hsa-miR-300 YES YES YES hsa-miR-338-3p YES YES YES hsa-miR-339-5p YES YES YES hsa-miR-381-3p YES YES YES hsa-miR-411-5p YES NO YES hsa-miR-488-3p YES YES YES hsa-miR-499a-5p YES YES NO hsa-miR-758-3p YES YES NO hsa-miR-876-5p YES YES NO hsa-miR-98-5p YES YES YES Display: