ctcRbase

Entry Detail

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General Information

Database ID: BRCA01478 Cancer Type: breast cancer Dataset: GSE55807 CTCs/CTM Isolation Method: CTC-iChip

Gene Information

ncRNA Symbol: TCP1 Full Name: t-complex 1 Category: mRNA Synonyms: CCT-alpha|CCT1|CCTa|D6S230E|TCP-1-alpha Chromosome: chr6 Strand: - Coordinate: Start Site(bp): 159778498 End Site(bp): 159789749 Gene Summary: The protein encoded by this gene is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternate transcriptional splice variants of this gene, encoding different isoforms, have been characterized. In addition, three pseudogenes that appear to be derived from this gene have been found. [provided by RefSeq, Jun 2010] External Links: Ensembl ID: ENSG00000120438 HGNC ID: HGNC:11655 Entrez Gene: 6950

Expression Profile of TCP1 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-10a-5p YES YES NO hsa-miR-10b-5p YES YES NO hsa-miR-185-5p YES YES NO hsa-miR-33a-5p YES YES NO hsa-miR-33b-5p YES YES NO hsa-miR-340-5p YES YES NO hsa-miR-488-3p YES YES NO hsa-miR-543 YES YES NO hsa-miR-758-3p YES YES NO Display: