ctcRbase

Entry Detail

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General Information

Database ID: BRCA01508 Cancer Type: breast cancer Dataset: GSE111065 CTCs/CTM Isolation Method: microfluidics immunofluorescence

Gene Information

ncRNA Symbol: OAT Full Name: ornithine aminotransferase Category: mRNA Synonyms: GACR|HOGA|OATASE|OKT Chromosome: chr10 Strand: - Coordinate: Start Site(bp): 124397303 End Site(bp): 124418976 Gene Summary: This gene encodes the mitochondrial enzyme ornithine aminotransferase, which is a key enzyme in the pathway that converts arginine and ornithine into the major excitatory and inhibitory neurotransmitters glutamate and GABA. Mutations that result in a deficiency of this enzyme cause the autosomal recessive eye disease Gyrate Atrophy. Alternatively spliced transcript variants encoding different isoforms have been described. Related pseudogenes have been defined on the X chromosome. [provided by RefSeq, Jan 2010] External Links: Ensembl ID: ENSG00000065154 HGNC ID: HGNC:8091 Entrez Gene: 4942

Expression Profile of OAT Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-1-3p YES YES NO hsa-miR-141-3p YES YES NO hsa-miR-186-5p YES YES NO hsa-miR-200a-3p YES YES NO hsa-miR-206 YES YES NO hsa-miR-384 YES YES NO hsa-miR-455-5p YES YES NO hsa-miR-485-5p YES YES NO hsa-miR-494-3p YES YES NO hsa-miR-543 YES YES NO hsa-miR-613 YES YES NO Display: