ctcRbase

Entry Detail

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General Information

Database ID: BRCA01564 Cancer Type: breast cancer Dataset: GSE41245 CTCs/CTM Isolation Method: CTC-Chip

Gene Information

ncRNA Symbol: ZNF280B Full Name: zinc finger protein 280B Category: mRNA Synonyms: 5'OY11.1|D87009.C22.3|SUHW2|ZNF279|ZNF632 Chromosome: chr22 Strand: - Coordinate: Start Site(bp): 22484421 End Site(bp): 22509154 Gene Summary: The protein encoded by this gene is a transcription factor that upregulates expression of MDM2, which negatively regulates p53 expression. This gene is highly expressed in prostate cancer cells, which leads to a reduction in p53 levels and an increase in growth of the cancer cells. Several transcript variants have been found for this gene, but only one of them is protein-coding. [provided by RefSeq, Jan 2015] External Links: Ensembl ID: ENSG00000275004 HGNC ID: HGNC:23022 Entrez Gene: 140883

Expression Profile of ZNF280B Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-let-7a-5p YES NO YES hsa-let-7b-5p YES NO YES hsa-let-7c-5p YES NO YES hsa-let-7d-5p YES NO YES hsa-let-7e-5p YES NO YES hsa-let-7f-5p YES NO YES hsa-let-7g-5p YES NO YES hsa-let-7i-5p YES NO YES hsa-miR-106a-5p YES YES YES hsa-miR-106b-5p YES YES YES hsa-miR-1271-5p YES YES YES hsa-miR-128-3p YES YES NO hsa-miR-129-2-3p YES NO YES hsa-miR-129-5p YES YES NO hsa-miR-139-5p YES YES NO hsa-miR-17-5p YES YES YES hsa-miR-181a-5p YES YES YES hsa-miR-181b-5p YES YES YES hsa-miR-181c-5p YES YES YES hsa-miR-181d-5p YES YES YES hsa-miR-182-5p YES YES YES hsa-miR-185-5p YES YES NO hsa-miR-18a-5p YES YES NO hsa-miR-18b-5p YES YES NO hsa-miR-199a-5p YES YES NO hsa-miR-199b-5p YES YES NO hsa-miR-19a-3p YES YES NO hsa-miR-19b-3p YES YES NO hsa-miR-20a-5p YES YES YES hsa-miR-20b-5p YES YES YES hsa-miR-30a-5p YES YES YES hsa-miR-30b-5p YES YES YES hsa-miR-30c-5p YES YES YES hsa-miR-30d-5p YES YES YES hsa-miR-30e-5p YES YES YES hsa-miR-329-3p YES NO NO hsa-miR-340-5p YES YES NO hsa-miR-362-3p YES NO NO hsa-miR-374a-5p YES YES NO hsa-miR-374b-5p YES YES NO hsa-miR-383-5p YES YES NO hsa-miR-491-5p YES YES NO hsa-miR-495-3p YES YES NO hsa-miR-519d-3p YES YES YES hsa-miR-873-5p YES YES NO hsa-miR-875-5p YES YES NO hsa-miR-93-5p YES YES YES hsa-miR-96-5p YES YES YES hsa-miR-98-5p YES NO YES Display: