ctcRbase

Entry Detail

---



General Information

Database ID: BRCA01637 Cancer Type: breast cancer Dataset: GSE55807 CTCs/CTM Isolation Method: CTC-iChip

Gene Information

ncRNA Symbol: PDCD6 Full Name: programmed cell death 6 Category: mRNA Synonyms: ALG-2|ALG2|PEF1B Chromosome: chr5 Strand: + Coordinate: Start Site(bp): 271621 End Site(bp): 353856 Gene Summary: This gene encodes a calcium-binding protein belonging to the penta-EF-hand protein family. Calcium binding is important for homodimerization and for conformational changes required for binding to other protein partners. This gene product participates in T cell receptor-, Fas-, and glucocorticoid-induced programmed cell death. In mice deficient for this gene product, however, apoptosis was not blocked suggesting this gene product is functionally redundant. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is also located on the short arm of chromosome 5. [provided by RefSeq, May 2012] External Links: Ensembl ID: ENSG00000249915 HGNC ID: HGNC:8765 Entrez Gene: 10016

Expression Profile of PDCD6 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-124-3p YES YES YES hsa-miR-129-5p YES YES NO hsa-miR-137 YES YES YES hsa-miR-183-5p YES YES YES hsa-miR-204-5p YES YES NO hsa-miR-211-5p YES YES NO hsa-miR-21-5p YES YES NO hsa-miR-23a-3p YES YES NO hsa-miR-23b-3p YES YES NO hsa-miR-384 YES YES NO hsa-miR-494-3p YES YES NO hsa-miR-506-3p YES YES YES hsa-miR-543 YES YES NO hsa-miR-590-5p YES YES NO hsa-miR-599 YES YES NO Display: