ctcRbase

Entry Detail

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General Information

Database ID: BRCA01784 Cancer Type: breast cancer Dataset: GSE111065 CTCs/CTM Isolation Method: microfluidics immunofluorescence

Gene Information

ncRNA Symbol: SUMO2 Full Name: small ubiquitin-like modifier 2 Category: mRNA Synonyms: HSMT3|SMT3B|SMT3H2|SUMO3|Smt3A Chromosome: chr17 Strand: - Coordinate: Start Site(bp): 75165586 End Site(bp): 75182983 Gene Summary: This gene encodes a protein that is a member of the SUMO (small ubiquitin-like modifier) protein family. It functions in a manner similar to ubiquitin in that it is bound to target proteins as part of a post-translational modification system. However, unlike ubiquitin which targets proteins for degradation, this protein is involved in a variety of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability. It is not active until the last two amino acids of the carboxy-terminus have been cleaved off. Numerous pseudogenes have been reported for this gene. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000188612 HGNC ID: HGNC:11125 Entrez Gene: 6613

Expression Profile of SUMO2 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-129-5p YES YES YES hsa-miR-132-3p YES YES NO hsa-miR-133a-3p YES YES NO hsa-miR-133b YES YES NO hsa-miR-1-3p YES YES NO hsa-miR-142-5p YES NO YES hsa-miR-186-5p YES YES NO hsa-miR-188-5p YES NO YES hsa-miR-194-5p YES YES YES hsa-miR-206 YES YES NO hsa-miR-212-3p YES YES NO hsa-miR-25-3p YES YES NO hsa-miR-27a-3p YES YES YES hsa-miR-27b-3p YES YES YES hsa-miR-32-5p YES YES NO hsa-miR-340-5p YES YES YES hsa-miR-363-3p YES YES NO hsa-miR-367-3p YES YES NO hsa-miR-488-3p YES YES NO hsa-miR-543 YES YES NO hsa-miR-613 YES YES NO hsa-miR-625-5p YES NO NO hsa-miR-874-3p YES YES YES hsa-miR-876-5p YES YES NO hsa-miR-92a-3p YES YES NO hsa-miR-92b-3p YES YES NO Display: