ctcRbase

Entry Detail

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General Information

Database ID: BRCA01809 Cancer Type: breast cancer Dataset: GSE111065 CTCs/CTM Isolation Method: microfluidics immunofluorescence

Gene Information

ncRNA Symbol: EZR Full Name: ezrin Category: mRNA Synonyms: CVIL|CVL|HEL-S-105|VIL2 Chromosome: chr6 Strand: - Coordinate: Start Site(bp): 158765741 End Site(bp): 158819412 Gene Summary: The cytoplasmic peripheral membrane protein encoded by this gene functions as a protein-tyrosine kinase substrate in microvilli. As a member of the ERM protein family, this protein serves as an intermediate between the plasma membrane and the actin cytoskeleton. This protein plays a key role in cell surface structure adhesion, migration and organization, and it has been implicated in various human cancers. A pseudogene located on chromosome 3 has been identified for this gene. Alternatively spliced variants have also been described for this gene. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000092820 HGNC ID: HGNC:12691 Entrez Gene: 7430

Expression Profile of EZR Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-1271-5p YES YES YES hsa-miR-148a-3p YES YES NO hsa-miR-148b-3p YES YES NO hsa-miR-152-3p YES YES NO hsa-miR-153-3p YES YES NO hsa-miR-183-5p YES YES YES hsa-miR-18a-5p YES YES NO hsa-miR-18b-5p YES YES NO hsa-miR-194-5p YES YES NO hsa-miR-204-5p YES YES YES hsa-miR-205-5p YES YES YES hsa-miR-211-5p YES YES YES hsa-miR-296-3p YES YES NO hsa-miR-338-3p YES YES NO hsa-miR-376a-3p YES YES YES hsa-miR-376b-3p YES YES YES hsa-miR-377-3p YES YES NO hsa-miR-409-3p YES NO YES hsa-miR-410-3p YES YES NO hsa-miR-495-3p YES YES NO hsa-miR-96-5p YES YES YES Display: