ctcRbase

Entry Detail

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General Information

Database ID: BRCA01825 Cancer Type: breast cancer Dataset: GSE55807 CTCs/CTM Isolation Method: CTC-iChip

Gene Information

ncRNA Symbol: CCT5 Full Name: chaperonin containing TCP1 subunit 5 Category: mRNA Synonyms: CCT-epsilon|CCTE|HEL-S-69|PNAS-102|TCP-1-epsilon Chromosome: chr5 Strand: + Coordinate: Start Site(bp): 10249921 End Site(bp): 10266412 Gene Summary: The protein encoded by this gene is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Mutations in this gene cause hereditary sensory and autonomic neuropathy with spastic paraplegia (HSNSP). Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 5 and 13. [provided by RefSeq, Apr 2015] External Links: Ensembl ID: ENSG00000150753 HGNC ID: HGNC:1618 Entrez Gene: 22948

Expression Profile of CCT5 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-103a-3p YES YES NO hsa-miR-107 YES YES NO hsa-miR-138-5p YES YES NO hsa-miR-139-5p YES YES YES hsa-miR-18a-5p YES YES NO hsa-miR-18b-5p YES YES NO hsa-miR-21-5p YES YES NO hsa-miR-221-3p YES YES NO hsa-miR-222-3p YES YES NO hsa-miR-328-3p YES YES NO hsa-miR-409-5p YES NO YES hsa-miR-494-3p YES YES NO hsa-miR-590-5p YES YES NO hsa-miR-873-5p YES YES NO Display: