ctcRbase

Entry Detail

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General Information

Database ID: BRCA01979 Cancer Type: breast cancer Dataset: GSE111065 CTCs/CTM Isolation Method: microfluidics immunofluorescence

Gene Information

ncRNA Symbol: SRSF2 Full Name: serine and arginine rich splicing factor 2 Category: mRNA Synonyms: PR264|SC-35|SC35|SFRS2|SFRS2A|SRp30b Chromosome: chr17 Strand: - Coordinate: Start Site(bp): 76734115 End Site(bp): 76737374 Gene Summary: The protein encoded by this gene is a member of the serine/arginine (SR)-rich family of pre-mRNA splicing factors, which constitute part of the spliceosome. Each of these factors contains an RNA recognition motif (RRM) for binding RNA and an RS domain for binding other proteins. The RS domain is rich in serine and arginine residues and facilitates interaction between different SR splicing factors. In addition to being critical for mRNA splicing, the SR proteins have also been shown to be involved in mRNA export from the nucleus and in translation. Two transcript variants encoding the same protein and one non-coding transcript variant have been found for this gene. In addition, a pseudogene of this gene has been found on chromosome 11. [provided by RefSeq, Sep 2010] External Links: Ensembl ID: ENSG00000161547 HGNC ID: HGNC:10783 Entrez Gene: 6427

Expression Profile of SRSF2 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-106a-5p YES YES NO hsa-miR-106b-5p YES YES NO hsa-miR-124-3p YES YES NO hsa-miR-1297 YES YES NO hsa-miR-130a-3p YES YES NO hsa-miR-130b-3p YES YES NO hsa-miR-134-5p YES YES YES hsa-miR-139-5p YES YES NO hsa-miR-1-3p YES YES NO hsa-miR-148a-3p YES YES NO hsa-miR-148b-3p YES YES NO hsa-miR-150-5p YES YES NO hsa-miR-152-3p YES YES NO hsa-miR-154-5p YES YES NO hsa-miR-17-5p YES YES NO hsa-miR-183-5p YES YES YES hsa-miR-186-5p YES YES NO hsa-miR-18a-5p YES YES NO hsa-miR-18b-5p YES YES NO hsa-miR-190a-5p YES YES NO hsa-miR-190b YES YES NO hsa-miR-193a-3p YES YES YES hsa-miR-193b-3p YES YES YES hsa-miR-200b-3p YES YES YES hsa-miR-200c-3p YES YES YES hsa-miR-206 YES YES NO hsa-miR-20a-5p YES YES NO hsa-miR-20b-5p YES YES NO hsa-miR-216b-5p YES YES NO hsa-miR-221-3p YES NO YES hsa-miR-222-3p YES NO YES hsa-miR-224-5p YES YES NO hsa-miR-26a-5p YES YES NO hsa-miR-26b-5p YES YES NO hsa-miR-28-5p YES YES NO hsa-miR-300 YES YES NO hsa-miR-301a-3p YES YES NO hsa-miR-301b-3p YES YES NO hsa-miR-320a YES YES NO hsa-miR-320b YES YES NO hsa-miR-320c YES YES NO hsa-miR-320d YES YES NO hsa-miR-338-3p YES YES YES hsa-miR-371a-5p YES YES NO hsa-miR-374a-5p YES YES NO hsa-miR-374b-5p YES YES NO hsa-miR-378a-3p YES YES NO hsa-miR-381-3p YES YES NO hsa-miR-383-5p YES YES NO hsa-miR-410-3p YES YES NO hsa-miR-422a YES YES NO hsa-miR-429 YES YES YES hsa-miR-454-3p YES YES NO hsa-miR-494-3p YES YES NO hsa-miR-495-3p YES YES NO hsa-miR-506-3p YES YES NO hsa-miR-519d-3p YES YES NO hsa-miR-543 YES YES NO hsa-miR-599 YES YES NO hsa-miR-613 YES YES NO hsa-miR-625-5p YES NO NO hsa-miR-708-5p YES YES NO hsa-miR-93-5p YES YES NO Display: