ctcRbase

Entry Detail

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General Information

Database ID: BRCA02037 Cancer Type: breast cancer Dataset: GSE109761 CTCs/CTM Isolation Method: microfluidics immunofluorescence

Gene Information

ncRNA Symbol: DEGS1 Full Name: delta 4-desaturase, sphingolipid 1 Category: mRNA Synonyms: DEGS|DEGS-1|DES1|Des-1|FADS7|MIG15|MLD Chromosome: chr1 Strand: + Coordinate: Start Site(bp): 224175756 End Site(bp): 224193441 Gene Summary: This gene encodes a member of the membrane fatty acid desaturase family which is responsible for inserting double bonds into specific positions in fatty acids. This protein contains three His-containing consensus motifs that are characteristic of a group of membrane fatty acid desaturases. It is predicted to be a multiple membrane-spanning protein localized to the endoplasmic reticulum. Overexpression of this gene inhibited biosynthesis of the EGF receptor, suggesting a possible role of a fatty acid desaturase in regulating biosynthetic processing of the EGF receptor. [provided by RefSeq, Mar 2010] External Links: Ensembl ID: ENSG00000143753 HGNC ID: HGNC:13709 Entrez Gene: 8560

Expression Profile of DEGS1 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-129-5p YES YES NO hsa-miR-143-3p YES YES NO hsa-miR-190a-5p YES YES NO hsa-miR-190b YES YES NO hsa-miR-194-5p YES YES NO hsa-miR-224-5p YES YES NO hsa-miR-340-5p YES YES NO hsa-miR-431-5p YES YES NO hsa-miR-494-3p YES YES NO hsa-miR-875-5p YES YES NO Display: