ctcRbase

Entry Detail

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General Information

Database ID: BRCA02043 Cancer Type: breast cancer Dataset: GSE41245 CTCs/CTM Isolation Method: CTC-Chip

Gene Information

ncRNA Symbol: ALDH6A1 Full Name: aldehyde dehydrogenase 6 family member A1 Category: mRNA Synonyms: MMSADHA|MMSDH Chromosome: chr14 Strand: - Coordinate: Start Site(bp): 74056850 End Site(bp): 74084493 Gene Summary: This gene encodes a member of the aldehyde dehydrogenase protein family. The encoded protein is a mitochondrial methylmalonate semialdehyde dehydrogenase that plays a role in the valine and pyrimidine catabolic pathways. This protein catalyzes the irreversible oxidative decarboxylation of malonate and methylmalonate semialdehydes to acetyl- and propionyl-CoA. Methylmalonate semialdehyde dehydrogenase deficiency is characterized by elevated beta-alanine, 3-hydroxypropionic acid, and both isomers of 3-amino and 3-hydroxyisobutyric acids in urine organic acids. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jun 2013] External Links: Ensembl ID: ENSG00000119711 HGNC ID: HGNC:7179 Entrez Gene: 4329

Expression Profile of ALDH6A1 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-132-3p YES YES NO hsa-miR-138-5p YES YES NO hsa-miR-149-5p YES YES NO hsa-miR-193a-3p YES YES NO hsa-miR-193b-3p YES YES NO hsa-miR-212-3p YES YES NO hsa-miR-320a YES YES NO hsa-miR-320b YES YES NO hsa-miR-320c YES YES NO hsa-miR-320d YES YES NO hsa-miR-376a-3p YES YES NO hsa-miR-376b-3p YES YES NO Display: