Entry Detail



General Information

Database ID:BRCA02097
Cancer Type:breast cancer
Dataset:GSE111065
CTCs/CTM Isolation Method:microfluidics immunofluorescence



Gene Information

ncRNA Symbol:HM13
Full Name:histocompatibility minor 13
Category:mRNA
Synonyms:H13|IMP1|IMPAS|IMPAS-1|MSTP086|PSENL3|PSL3|SPP|SPPL1
Chromosome:chr20
Strand:+
Coordinate:
Start Site(bp):31514428End Site(bp):31577923
Gene Summary:The protein encoded by this gene, which localizes to the endoplasmic reticulum, catalyzes intramembrane proteolysis of some signal peptides after they have been cleaved from a preprotein. This activity is required to generate signal sequence-derived human lymphocyte antigen-E epitopes that are recognized by the immune system, and to process hepatitis C virus core protein. The encoded protein is an integral membrane protein with sequence motifs characteristic of the presenilin-type aspartic proteases. Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
External Links:
Ensembl ID:ENSG00000101294
HGNC ID:HGNC:16435
Entrez Gene:81502



Expression Profile of HM13 Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-miR-139-5p
YES
YES
NO
hsa-miR-149-5p
YES
YES
NO
hsa-miR-328-3p
YES
NO
YES
hsa-miR-455-3p
YES
NO
YES
hsa-miR-490-3p
YES
YES
NO
hsa-miR-491-5p
YES
YES
NO
hsa-miR-668-3p
YES
NO
YES
hsa-miR-9-5p
YES
YES
YES
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