Entry Detail



General Information

Database ID:BRCA02141
Cancer Type:breast cancer
Dataset:GSE109761
CTCs/CTM Isolation Method:microfluidics immunofluorescence



Gene Information

ncRNA Symbol:F11R
Full Name:F11 receptor
Category:mRNA
Synonyms:CD321|JAM|JAM1|JAMA|JCAM|KAT|PAM-1
Chromosome:chr1
Strand:-
Coordinate:
Start Site(bp):160995211End Site(bp):161021348
Gene Summary:Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is an important regulator of tight junction assembly in epithelia. In addition, the encoded protein can act as (1) a receptor for reovirus, (2) a ligand for the integrin LFA1, involved in leukocyte transmigration, and (3) a platelet receptor. Multiple 5' alternatively spliced variants, encoding the same protein, have been identified but their biological validity has not been established. [provided by RefSeq, Jul 2008]
External Links:
Ensembl ID:ENSG00000158769
HGNC ID:HGNC:14685
Entrez Gene:50848



Expression Profile of F11R Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-miR-124-3p
YES
NO
YES
hsa-miR-145-5p
YES
YES
NO
hsa-miR-181b-5p
YES
YES
NO
hsa-miR-181c-5p
YES
YES
NO
hsa-miR-181d-5p
YES
YES
NO
hsa-miR-186-5p
YES
NO
NO
hsa-miR-216a-5p
YES
NO
YES
hsa-miR-216b-5p
YES
NO
YES
hsa-miR-29a-3p
YES
NO
YES
hsa-miR-29b-3p
YES
NO
YES
hsa-miR-29c-3p
YES
NO
YES
hsa-miR-329-3p
YES
NO
NO
hsa-miR-338-3p
YES
NO
YES
hsa-miR-340-5p
YES
YES
NO
hsa-miR-362-3p
YES
NO
NO
hsa-miR-376c-3p
YES
YES
NO
hsa-miR-425-5p
YES
YES
NO
hsa-miR-489-3p
YES
NO
YES
hsa-miR-494-3p
YES
YES
YES
hsa-miR-495-3p
YES
YES
NO
hsa-miR-503-5p
YES
YES
NO
hsa-miR-506-3p
YES
NO
YES
hsa-miR-543
YES
YES
NO
hsa-miR-876-5p
YES
YES
NO
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