ctcRbase

Entry Detail

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General Information

Database ID: BRCA02203 Cancer Type: breast cancer Dataset: GSE109761 CTCs/CTM Isolation Method: microfluidics immunofluorescence

Gene Information

ncRNA Symbol: PPP2R1A Full Name: protein phosphatase 2 scaffold subunit Aalpha Category: mRNA Synonyms: MRD36|PP2A-Aalpha|PP2AA|PP2AAALPHA|PR65A Chromosome: chr19 Strand: + Coordinate: Start Site(bp): 52190039 End Site(bp): 52229533 Gene Summary: This gene encodes a constant regulatory subunit of protein phosphatase 2. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The constant regulatory subunit A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. This gene encodes an alpha isoform of the constant regulatory subunit A. Alternatively spliced transcript variants have been described. [provided by RefSeq, Apr 2010] External Links: Ensembl ID: ENSG00000105568 HGNC ID: HGNC:9302 Entrez Gene: 5518

Expression Profile of PPP2R1A Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-150-5p YES YES NO hsa-miR-15a-5p YES YES YES hsa-miR-15b-5p YES YES YES hsa-miR-16-5p YES YES YES hsa-miR-195-5p YES YES YES hsa-miR-199a-5p YES YES NO hsa-miR-199b-5p YES YES NO hsa-miR-214-3p YES YES NO hsa-miR-329-3p YES YES NO hsa-miR-362-3p YES YES NO hsa-miR-424-5p YES YES YES hsa-miR-497-5p YES YES YES hsa-miR-542-3p YES YES YES hsa-miR-625-5p YES NO NO Display: