ctcRbase

Entry Detail

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General Information

Database ID: BRCA02231 Cancer Type: breast cancer Dataset: GSE111842 CTCs/CTM Isolation Method: immunomagnetic FACS

Gene Information

ncRNA Symbol: FTO Full Name: FTO, alpha-ketoglutarate dependent dioxygenase Category: mRNA Synonyms: ALKBH9|BMIQ14|GDFD Chromosome: chr16 Strand: + Coordinate: Start Site(bp): 53701692 End Site(bp): 54158512 Gene Summary: This gene is a nuclear protein of the AlkB related non-haem iron and 2-oxoglutarate-dependent oxygenase superfamily but the exact physiological function of this gene is not known. Other non-heme iron enzymes function to reverse alkylated DNA and RNA damage by oxidative demethylation. Studies in mice and humans indicate a role in nervous and cardiovascular systems and a strong association with body mass index, obesity risk, and type 2 diabetes. [provided by RefSeq, Jul 2011] External Links: Ensembl ID: ENSG00000140718 HGNC ID: HGNC:24678 Entrez Gene: 79068

Expression Profile of FTO Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-101-3p YES YES NO hsa-miR-138-5p YES YES NO hsa-miR-148a-3p YES YES NO hsa-miR-148b-3p YES YES NO hsa-miR-150-5p YES YES YES hsa-miR-152-3p YES YES NO hsa-miR-185-5p YES YES NO hsa-miR-186-5p YES NO NO hsa-miR-190b YES YES NO hsa-miR-217 YES YES NO hsa-miR-377-3p YES YES NO hsa-miR-410-3p YES YES NO hsa-miR-488-3p YES YES NO Display: