ctcRbase

Entry Detail

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General Information

Database ID: BRCA02245 Cancer Type: breast cancer Dataset: GSE111065 CTCs/CTM Isolation Method: microfluidics immunofluorescence

Gene Information

ncRNA Symbol: HMGB1 Full Name: high mobility group box 1 Category: mRNA Synonyms: HMG-1|HMG1|HMG3|SBP-1 Chromosome: chr13 Strand: - Coordinate: Start Site(bp): 30456704 End Site(bp): 30617597 Gene Summary: This gene encodes a protein that belongs to the High Mobility Group-box superfamily. The encoded non-histone, nuclear DNA-binding protein regulates transcription, and is involved in organization of DNA. This protein plays a role in several cellular processes, including inflammation, cell differentiation and tumor cell migration. Multiple pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Sep 2015] External Links: Ensembl ID: ENSG00000189403 HGNC ID: HGNC:4983 Entrez Gene: 3146

Expression Profile of HMGB1 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-105-5p YES NO NO hsa-miR-122-5p YES YES NO hsa-miR-129-5p NO YES YES hsa-miR-140-5p YES YES NO hsa-miR-141-3p YES YES YES hsa-miR-142-3p YES YES YES hsa-miR-181a-5p YES NO YES hsa-miR-181b-5p YES NO YES hsa-miR-181c-5p YES NO YES hsa-miR-181d-5p YES NO YES hsa-miR-186-5p YES YES YES hsa-miR-193a-3p YES YES NO hsa-miR-193b-3p YES YES NO hsa-miR-200a-3p YES YES YES hsa-miR-200b-3p YES YES NO hsa-miR-200c-3p YES YES NO hsa-miR-204-5p NO YES YES hsa-miR-205-5p YES NO YES hsa-miR-211-5p NO YES YES hsa-miR-216a-5p YES YES YES hsa-miR-216b-5p YES YES YES hsa-miR-218-5p YES YES YES hsa-miR-22-3p YES YES NO hsa-miR-25-3p YES YES NO hsa-miR-300 YES YES YES hsa-miR-34a-5p YES YES YES hsa-miR-34c-5p YES YES YES hsa-miR-370-3p YES YES NO hsa-miR-381-3p YES YES YES hsa-miR-383-5p YES YES NO hsa-miR-410-3p YES YES YES hsa-miR-429 YES YES NO hsa-miR-449a YES YES YES hsa-miR-449b-5p YES YES YES hsa-miR-488-3p YES YES NO hsa-miR-490-3p YES YES NO hsa-miR-495-3p YES YES NO hsa-miR-496 YES YES NO hsa-miR-505-3p YES YES YES hsa-miR-582-5p YES NO YES hsa-miR-665 YES NO YES hsa-miR-92a-3p YES YES NO Display: