ctcRbase

Entry Detail

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General Information

Database ID: BRCA02281 Cancer Type: breast cancer Dataset: GSE41245 CTCs/CTM Isolation Method: CTC-Chip

Gene Information

ncRNA Symbol: XYLT2 Full Name: xylosyltransferase 2 Category: mRNA Synonyms: PXYLT2|SOS|XT-II|XT2|xylT-II Chromosome: chr17 Strand: + Coordinate: Start Site(bp): 50346092 End Site(bp): 50363138 Gene Summary: The protein encoded by this gene is an isoform of xylosyltransferase, which belongs to a family of glycosyltransferases. This enzyme transfers xylose from UDP-xylose to specific serine residues of the core protein and initiates the biosynthesis of glycosaminoglycan chains in proteoglycans including chondroitin sulfate, heparan sulfate, heparin and dermatan sulfate. The enzyme activity, which is increased in scleroderma patients, is a diagnostic marker for the determination of sclerotic activity in systemic sclerosis. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Dec 2013] External Links: Ensembl ID: ENSG00000015532 HGNC ID: HGNC:15517 Entrez Gene: 64132

Expression Profile of XYLT2 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-138-5p YES YES NO hsa-miR-150-5p YES YES NO hsa-miR-153-3p YES YES YES hsa-miR-186-5p YES YES NO hsa-miR-18a-5p YES YES YES hsa-miR-18b-5p YES YES YES hsa-miR-25-3p YES YES YES hsa-miR-32-5p YES YES YES hsa-miR-363-3p YES YES YES hsa-miR-367-3p YES YES YES hsa-miR-431-5p YES YES NO hsa-miR-448 YES YES YES hsa-miR-92a-3p YES YES YES hsa-miR-92b-3p YES YES YES Display: