ctcRbase

Entry Detail

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General Information

Database ID: BRCA02338 Cancer Type: breast cancer Dataset: GSE109761 CTCs/CTM Isolation Method: microfluidics immunofluorescence

Gene Information

ncRNA Symbol: RBBP4 Full Name: RB binding protein 4, chromatin remodeling factor Category: mRNA Synonyms: NURF55|RBAP48|lin-53 Chromosome: chr1 Strand: + Coordinate: Start Site(bp): 32651142 End Site(bp): 32686211 Gene Summary: This gene encodes a ubiquitously expressed nuclear protein which belongs to a highly conserved subfamily of WD-repeat proteins. It is present in protein complexes involved in histone acetylation and chromatin assembly. It is part of the Mi-2 complex which has been implicated in chromatin remodeling and transcriptional repression associated with histone deacetylation. This encoded protein is also part of co-repressor complexes, which is an integral component of transcriptional silencing. It is found among several cellular proteins that bind directly to retinoblastoma protein to regulate cell proliferation. This protein also seems to be involved in transcriptional repression of E2F-responsive genes. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2008] External Links: Ensembl ID: ENSG00000162521 HGNC ID: HGNC:9887 Entrez Gene: 5928

Expression Profile of RBBP4 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-138-5p YES NO YES hsa-miR-194-5p YES NO YES hsa-miR-199a-5p YES NO YES hsa-miR-199b-5p YES NO YES hsa-miR-24-3p YES YES YES hsa-miR-300 YES YES NO hsa-miR-377-3p YES YES NO hsa-miR-381-3p YES YES NO Display: