ctcRbase

Entry Detail

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General Information

Database ID: BRCA02379 Cancer Type: breast cancer Dataset: GSE111065 CTCs/CTM Isolation Method: microfluidics immunofluorescence

Gene Information

ncRNA Symbol: XRCC5 Full Name: X-ray repair cross complementing 5 Category: mRNA Synonyms: KARP-1|KARP1|KU80|KUB2|Ku86|NFIV Chromosome: chr2 Strand: + Coordinate: Start Site(bp): 216107464 End Site(bp): 216206303 Gene Summary: The protein encoded by this gene is the 80-kilodalton subunit of the Ku heterodimer protein which is also known as ATP-dependant DNA helicase II or DNA repair protein XRCC5. Ku is the DNA-binding component of the DNA-dependent protein kinase, and it functions together with the DNA ligase IV-XRCC4 complex in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events. This gene functionally complements Chinese hamster xrs-6, a mutant defective in DNA double-strand break repair and in ability to undergo V(D)J recombination. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000079246 HGNC ID: HGNC:12833 Entrez Gene: 7520

Expression Profile of XRCC5 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-134-5p YES YES NO hsa-miR-188-5p YES NO YES hsa-miR-204-5p YES YES NO hsa-miR-211-5p YES YES NO hsa-miR-31-5p YES YES NO hsa-miR-320a YES YES NO hsa-miR-320b YES YES NO hsa-miR-320c YES YES NO hsa-miR-320d YES YES NO hsa-miR-330-3p YES NO YES hsa-miR-340-5p YES NO YES hsa-miR-370-3p YES YES NO hsa-miR-382-5p YES YES NO hsa-miR-410-3p YES YES NO hsa-miR-532-5p YES NO YES hsa-miR-542-3p YES YES NO hsa-miR-758-3p YES YES NO Display: