ctcRbase

Entry Detail

---



General Information

Database ID: BRCA02409 Cancer Type: breast cancer Dataset: GSE109761 CTCs/CTM Isolation Method: microfluidics immunofluorescence

Gene Information

ncRNA Symbol: CD151 Full Name: CD151 molecule (Raph blood group) Category: mRNA Synonyms: GP27|MER2|PETA-3|RAPH|SFA1|TSPAN24 Chromosome: chr11 Strand: + Coordinate: Start Site(bp): 832843 End Site(bp): 839831 Gene Summary: The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins and other transmembrane 4 superfamily proteins. It is involved in cellular processes including cell adhesion and may regulate integrin trafficking and/or function. This protein enhances cell motility, invasion and metastasis of cancer cells. Multiple alternatively spliced transcript variants that encode the same protein have been described for this gene. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000177697 HGNC ID: HGNC:1630 Entrez Gene: 977

Expression Profile of CD151 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-103a-3p YES NO NO hsa-miR-107 YES NO NO hsa-miR-124-3p YES YES YES hsa-miR-128-3p YES YES NO hsa-miR-15a-5p YES NO NO hsa-miR-15b-5p YES NO NO hsa-miR-16-5p YES NO NO hsa-miR-183-5p YES YES NO hsa-miR-195-5p YES NO NO hsa-miR-199a-3p YES NO YES hsa-miR-199b-3p YES NO YES hsa-miR-214-3p YES YES NO hsa-miR-22-3p YES YES NO hsa-miR-424-5p YES NO NO hsa-miR-497-5p YES NO NO hsa-miR-506-3p YES YES NO Display: