ctcRbase

Entry Detail

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General Information

Database ID: BRCA02430 Cancer Type: breast cancer Dataset: GSE41245 CTCs/CTM Isolation Method: CTC-Chip

Gene Information

ncRNA Symbol: ME2 Full Name: malic enzyme 2 Category: mRNA Synonyms: ODS1 Chromosome: chr18 Strand: + Coordinate: Start Site(bp): 50878734 End Site(bp): 50954257 Gene Summary: This gene encodes a mitochondrial NAD-dependent malic enzyme, a homotetrameric protein, that catalyzes the oxidative decarboxylation of malate to pyruvate. It had previously been weakly linked to a syndrome known as Friedreich ataxia that has since been shown to be the result of mutation in a completely different gene. Certain single-nucleotide polymorphism haplotypes of this gene have been shown to increase the risk for idiopathic generalized epilepsy. Alternatively spliced transcript variants encoding different isoforms found for this gene. [provided by RefSeq, Dec 2009] External Links: Ensembl ID: ENSG00000082212 HGNC ID: HGNC:6984 Entrez Gene: 4200

Expression Profile of ME2 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-181a-5p YES YES NO hsa-miR-181b-5p YES YES NO hsa-miR-181c-5p YES YES NO hsa-miR-181d-5p YES YES NO hsa-miR-182-5p NO YES YES hsa-miR-371a-5p YES YES NO hsa-miR-410-3p YES YES NO hsa-miR-425-5p YES YES NO hsa-miR-496 YES YES NO hsa-miR-653-5p YES YES NO Display: