ctcRbase

Entry Detail

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General Information

Database ID: BRCA02473 Cancer Type: breast cancer Dataset: GSE55807 CTCs/CTM Isolation Method: CTC-iChip

Gene Information

ncRNA Symbol: DYNLRB1 Full Name: dynein light chain roadblock-type 1 Category: mRNA Synonyms: BITH|BLP|DNCL2A|DNLC2A|ROBLD1 Chromosome: chr20 Strand: + Coordinate: Start Site(bp): 34516409 End Site(bp): 34540958 Gene Summary: This gene is a member of the roadblock dynein light chain family. The encoded cytoplasmic protein is capable of binding intermediate chain proteins, interacts with transforming growth factor-beta, and has been implicated in the regulation of actin modulating proteins. Upregulation of this gene has been associated with hepatocellular carcinomas, suggesting that this gene may be involved in tumor progression. Alternative splicing results in multiple transcript variants. Pseudogenes of this gene have been defined on chromosomes 12 and 18. [provided by RefSeq, Aug 2013] External Links: Ensembl ID: ENSG00000125971 HGNC ID: HGNC:15468 Entrez Gene: 83658

Expression Profile of DYNLRB1 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-1-3p YES YES NO hsa-miR-186-5p YES YES YES hsa-miR-206 YES YES NO hsa-miR-425-5p YES YES NO hsa-miR-490-3p YES YES NO hsa-miR-493-3p YES NO YES hsa-miR-543 YES YES NO hsa-miR-613 YES YES NO Display: