ctcRbase

Entry Detail

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General Information

Database ID: BRCA02481 Cancer Type: breast cancer Dataset: GSE55807 CTCs/CTM Isolation Method: CTC-iChip

Gene Information

ncRNA Symbol: RNF7 Full Name: ring finger protein 7 Category: mRNA Synonyms: CKBBP1|ROC2|SAG|rbx2 Chromosome: chr3 Strand: + Coordinate: Start Site(bp): 141738204 End Site(bp): 141747560 Gene Summary: The protein encoded by this gene is a highly conserved ring finger protein. It is an essential subunit of SKP1-cullin/CDC53-F box protein ubiquitin ligases, which are a part of the protein degradation machinery important for cell cycle progression and signal transduction. This protein interacts with, and is a substrate of, casein kinase II (CSNK2A1/CKII). The phosphorylation of this protein by CSNK2A1 has been shown to promote the degradation of IkappaBalpha (CHUK/IKK-alpha/IKBKA) and p27Kip1(CDKN1B). Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000114125 HGNC ID: HGNC:10070 Entrez Gene: 9616

Expression Profile of RNF7 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-let-7a-5p YES YES YES hsa-let-7b-5p YES YES YES hsa-let-7c-5p YES YES YES hsa-let-7d-5p YES YES YES hsa-let-7e-5p YES YES YES hsa-let-7f-5p YES YES YES hsa-let-7g-5p YES YES YES hsa-let-7i-5p YES YES YES hsa-miR-140-3p YES NO YES hsa-miR-142-3p YES YES NO hsa-miR-18a-5p YES YES NO hsa-miR-18b-5p YES YES NO hsa-miR-194-5p YES YES NO hsa-miR-217 YES YES NO hsa-miR-329-3p YES YES NO hsa-miR-340-5p YES YES YES hsa-miR-362-3p YES YES NO hsa-miR-370-3p YES YES YES hsa-miR-543 YES YES NO hsa-miR-9-5p YES NO YES hsa-miR-98-5p YES YES YES Display: