ctcRbase

Entry Detail

---



General Information

Database ID: BRCA02506 Cancer Type: breast cancer Dataset: GSE55807 CTCs/CTM Isolation Method: CTC-iChip

Gene Information

ncRNA Symbol: CDKN3 Full Name: cyclin dependent kinase inhibitor 3 Category: mRNA Synonyms: CDI1|CIP2|KAP|KAP1 Chromosome: chr14 Strand: + Coordinate: Start Site(bp): 54396849 End Site(bp): 54420218 Gene Summary: The protein encoded by this gene belongs to the dual specificity protein phosphatase family. It was identified as a cyclin-dependent kinase inhibitor, and has been shown to interact with, and dephosphorylate CDK2 kinase, thus prevent the activation of CDK2 kinase. This gene was reported to be deleted, mutated, or overexpressed in several kinds of cancers. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008] External Links: Ensembl ID: ENSG00000100526 HGNC ID: HGNC:1791 Entrez Gene: 1033

Expression Profile of CDKN3 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-1297 YES YES NO hsa-miR-135a-5p NO YES YES hsa-miR-135b-5p NO YES YES hsa-miR-141-3p YES YES NO hsa-miR-146a-5p YES YES NO hsa-miR-146b-5p YES YES NO hsa-miR-181a-5p YES YES NO hsa-miR-181b-5p YES YES NO hsa-miR-181c-5p YES YES NO hsa-miR-181d-5p YES YES NO hsa-miR-200a-3p YES YES NO hsa-miR-26a-5p YES YES NO hsa-miR-26b-5p YES YES NO hsa-miR-300 YES YES NO hsa-miR-382-5p YES YES NO Display: