ctcRbase

Entry Detail

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General Information

Database ID: BRCA02530 Cancer Type: breast cancer Dataset: GSE55807 CTCs/CTM Isolation Method: CTC-iChip

Gene Information

ncRNA Symbol: MRPL27 Full Name: mitochondrial ribosomal protein L27 Category: mRNA Synonyms: L27mt Chromosome: chr17 Strand: - Coordinate: Start Site(bp): 50367857 End Site(bp): 50373214 Gene Summary: Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000108826 HGNC ID: HGNC:14483 Entrez Gene: 51264

Expression Profile of MRPL27 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-149-5p YES YES NO hsa-miR-150-5p YES YES NO hsa-miR-18a-5p YES YES YES hsa-miR-18b-5p YES YES YES hsa-miR-330-3p YES NO YES hsa-miR-342-3p YES YES NO hsa-miR-383-5p YES YES NO hsa-miR-421 YES YES NO hsa-miR-873-5p YES YES NO Display: