ctcRbase

Entry Detail

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General Information

Database ID: BRCA02548 Cancer Type: breast cancer Dataset: GSE55807 CTCs/CTM Isolation Method: CTC-iChip

Gene Information

ncRNA Symbol: PCBD1 Full Name: pterin-4 alpha-carbinolamine dehydratase 1 Category: mRNA Synonyms: DCOH|PCBD|PCD|PHS Chromosome: chr10 Strand: - Coordinate: Start Site(bp): 70882280 End Site(bp): 70888784 Gene Summary: This gene encodes a member of the pterin-4-alpha-carbinolamine dehydratase family. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. The encoded protein functions as both a dehydratase involved in tetrahydrobiopterin biosynthesis, and as a cofactor for HNF1A-dependent transcription. A deficiency of this enzyme leads to hyperphenylalaninemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014] External Links: Ensembl ID: ENSG00000166228 HGNC ID: HGNC:8646 Entrez Gene: 5092

Expression Profile of PCBD1 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-10a-5p YES YES NO hsa-miR-10b-5p YES YES NO hsa-miR-185-5p YES YES NO hsa-miR-194-5p YES YES YES hsa-miR-31-5p YES YES NO hsa-miR-374a-5p YES YES NO hsa-miR-374b-5p YES YES NO hsa-miR-410-3p YES YES NO hsa-miR-491-5p YES YES NO Display: