ctcRbase

Entry Detail

---



General Information

Database ID: BRCA02587 Cancer Type: breast cancer Dataset: GSE111065 CTCs/CTM Isolation Method: microfluidics immunofluorescence

Gene Information

ncRNA Symbol: SLC9A3R1 Full Name: SLC9A3 regulator 1 Category: mRNA Synonyms: EBP50|NHERF|NHERF-1|NHERF1|NPHLOP2 Chromosome: chr17 Strand: + Coordinate: Start Site(bp): 74748652 End Site(bp): 74769353 Gene Summary: This gene encodes a sodium/hydrogen exchanger regulatory cofactor. The protein interacts with and regulates various proteins including the cystic fibrosis transmembrane conductance regulator and G-protein coupled receptors such as the beta2-adrenergic receptor and the parathyroid hormone 1 receptor. The protein also interacts with proteins that function as linkers between integral membrane and cytoskeletal proteins. The protein localizes to actin-rich structures including membrane ruffles, microvilli, and filopodia. Mutations in this gene result in hypophosphatemic nephrolithiasis/osteoporosis type 2, and loss of heterozygosity of this gene is implicated in breast cancer.[provided by RefSeq, Sep 2009] External Links: Ensembl ID: ENSG00000109062 HGNC ID: HGNC:11075 Entrez Gene: 9368

Expression Profile of SLC9A3R1 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-149-5p YES YES YES hsa-miR-187-3p YES YES NO hsa-miR-200b-3p YES YES NO hsa-miR-200c-3p YES YES NO hsa-miR-217 YES YES NO hsa-miR-24-3p YES YES YES hsa-miR-299-3p YES YES NO hsa-miR-346 YES YES NO hsa-miR-429 YES YES NO hsa-miR-874-3p YES YES NO Display: