ctcRbase

Entry Detail

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General Information

Database ID: BRCA02603 Cancer Type: breast cancer Dataset: GSE109761 CTCs/CTM Isolation Method: microfluidics immunofluorescence

Gene Information

ncRNA Symbol: ATP1B3 Full Name: ATPase Na+/K+ transporting subunit beta 3 Category: mRNA Synonyms: ATPB-3|CD298 Chromosome: chr3 Strand: + Coordinate: Start Site(bp): 141876124 End Site(bp): 141926514 Gene Summary: The protein encoded by this gene belongs to the family of Na+/K+ and H+/K+ ATPases beta chain proteins, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane. The glycoprotein subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes a beta 3 subunit. This gene encodes a beta 3 subunit. A pseudogene exists for this gene, and it is located on chromosome 2. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000069849 HGNC ID: HGNC:806 Entrez Gene: 483

Expression Profile of ATP1B3 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-1197 YES NO YES hsa-miR-182-5p YES YES YES hsa-miR-218-5p YES YES NO hsa-miR-224-5p YES YES YES hsa-miR-329-3p YES YES NO hsa-miR-340-5p YES YES NO hsa-miR-362-3p YES YES NO hsa-miR-376c-3p YES YES NO hsa-miR-425-5p YES YES YES hsa-miR-653-5p YES YES NO Display: