Entry Detail



General Information

Database ID:BRCA02610
Cancer Type:breast cancer
Dataset:GSE55807
CTCs/CTM Isolation Method:CTC-iChip



Gene Information

ncRNA Symbol:FDFT1
Full Name:farnesyl-diphosphate farnesyltransferase 1
Category:mRNA
Synonyms:DGPT|ERG9|SQS|SQSD|SS
Chromosome:chr8
Strand:+
Coordinate:
Start Site(bp):11795573End Site(bp):11839309
Gene Summary:This gene encodes a membrane-associated enzyme located at a branch point in the mevalonate pathway. The encoded protein is the first specific enzyme in cholesterol biosynthesis, catalyzing the dimerization of two molecules of farnesyl diphosphate in a two-step reaction to form squalene. [provided by RefSeq, Jul 2008]
External Links:
Ensembl ID:ENSG00000079459
HGNC ID:HGNC:3629
Entrez Gene:2222



Expression Profile of FDFT1 Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-miR-128-3p
YES
YES
NO
hsa-miR-136-5p
YES
YES
NO
hsa-miR-181a-5p
YES
YES
NO
hsa-miR-181b-5p
YES
YES
NO
hsa-miR-181c-5p
YES
YES
NO
hsa-miR-181d-5p
YES
YES
NO
hsa-miR-186-5p
YES
YES
NO
hsa-miR-200b-3p
YES
YES
NO
hsa-miR-200c-3p
YES
YES
NO
hsa-miR-216a-5p
YES
YES
YES
hsa-miR-216b-5p
YES
YES
YES
hsa-miR-23a-3p
YES
YES
NO
hsa-miR-23b-3p
YES
YES
NO
hsa-miR-28-5p
YES
YES
NO
hsa-miR-340-5p
YES
YES
NO
hsa-miR-370-3p
YES
YES
NO
hsa-miR-371a-5p
YES
YES
NO
hsa-miR-429
YES
YES
NO
hsa-miR-494-3p
YES
YES
NO
hsa-miR-543
YES
YES
NO
hsa-miR-708-5p
YES
YES
NO
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