| ncRNA Symbol: | SRD5A3 |
| Full Name: | steroid 5 alpha-reductase 3 |
| Category: | mRNA |
| Synonyms: | CDG1P|CDG1Q|KRIZI|SRD5A2L|SRD5A2L1 |
| Chromosome: | chr4 |
| Strand: | + |
| Coordinate: | | Start Site(bp): | 55346109 | End Site(bp): | 55373096 |
|
| Gene Summary: | The protein encoded by this gene belongs to the steroid 5-alpha reductase family, and polyprenol reductase subfamily. It is involved in the production of androgen 5-alpha-dihydrotestosterone (DHT) from testosterone, and maintenance of the androgen-androgen receptor activation pathway. This protein is also necessary for the conversion of polyprenol into dolichol, which is required for the synthesis of dolichol-linked monosaccharides and the oligosaccharide precursor used for N-linked glycosylation of proteins. Mutations in this gene are associated with congenital disorder of glycosylation type Iq. [provided by RefSeq, Mar 2011] |
| External Links: | |