ctcRbase

Entry Detail

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General Information

Database ID: BRCA02665 Cancer Type: breast cancer Dataset: GSE109761 CTCs/CTM Isolation Method: microfluidics immunofluorescence

Gene Information

ncRNA Symbol: SDHC Full Name: succinate dehydrogenase complex subunit C Category: mRNA Synonyms: CYB560|CYBL|PGL3|QPS1|SDH3 Chromosome: chr1 Strand: + Coordinate: Start Site(bp): 161314257 End Site(bp): 161375340 Gene Summary: This gene encodes one of four nuclear-encoded subunits that comprise succinate dehydrogenase, also known as mitochondrial complex II, a key enzyme complex of the tricarboxylic acid cycle and aerobic respiratory chains of mitochondria. The encoded protein is one of two integral membrane proteins that anchor other subunits of the complex, which form the catalytic core, to the inner mitochondrial membrane. There are several related pseudogenes for this gene on different chromosomes. Mutations in this gene have been associated with paragangliomas. Alternatively spliced transcript variants have been described. [provided by RefSeq, May 2013] External Links: Ensembl ID: ENSG00000143252 HGNC ID: HGNC:10682 Entrez Gene: 6391

Expression Profile of SDHC Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-1251-5p YES NO YES hsa-miR-129-5p YES YES NO hsa-miR-140-5p YES YES NO hsa-miR-141-3p YES YES NO hsa-miR-146a-5p YES YES NO hsa-miR-146b-5p YES YES NO hsa-miR-15a-5p YES YES NO hsa-miR-15b-5p YES YES NO hsa-miR-16-5p YES YES NO hsa-miR-185-5p YES YES YES hsa-miR-195-5p YES YES NO hsa-miR-200a-3p YES YES NO hsa-miR-21-5p YES YES NO hsa-miR-216a-5p YES NO YES hsa-miR-216b-5p YES YES YES hsa-miR-223-3p YES YES NO hsa-miR-320a YES YES YES hsa-miR-320b YES YES YES hsa-miR-320c YES YES YES hsa-miR-320d YES YES YES hsa-miR-326 YES YES NO hsa-miR-330-5p YES YES NO hsa-miR-424-5p YES YES NO hsa-miR-496 YES YES YES hsa-miR-497-5p YES YES NO hsa-miR-542-3p YES YES NO hsa-miR-551a YES YES NO hsa-miR-551b-3p YES YES NO hsa-miR-590-5p YES YES NO hsa-miR-7-5p YES YES NO Display: