ctcRbase

Entry Detail

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General Information

Database ID: BRCA02756 Cancer Type: breast cancer Dataset: GSE55807 CTCs/CTM Isolation Method: CTC-iChip

Gene Information

ncRNA Symbol: MRPL48 Full Name: mitochondrial ribosomal protein L48 Category: mRNA Synonyms: CGI-118|HSPC290|L48MT|MRP-L48 Chromosome: chr11 Strand: + Coordinate: Start Site(bp): 73787316 End Site(bp): 73865133 Gene Summary: Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. A pseudogene corresponding to this gene is found on chromosome 6p. Several transcript variants, some protein-coding and some non-protein coding, have been found for this gene. [provided by RefSeq, Jan 2016] External Links: Ensembl ID: ENSG00000175581 HGNC ID: HGNC:16653 Entrez Gene: 51642

Expression Profile of MRPL48 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-103a-3p YES YES NO hsa-miR-107 YES YES NO hsa-miR-1271-5p YES YES NO hsa-miR-193a-3p YES YES NO hsa-miR-193b-3p YES YES NO hsa-miR-214-3p YES YES NO hsa-miR-296-3p YES YES NO hsa-miR-31-5p YES NO YES hsa-miR-7-5p YES YES NO hsa-miR-9-5p YES YES NO hsa-miR-96-5p YES YES NO Display: