| ncRNA Symbol: | POLR2E |
| Full Name: | RNA polymerase II subunit E |
| Category: | mRNA |
| Synonyms: | RPABC1|RPB5|XAP4|hRPB25|hsRPB5 |
| Chromosome: | chr19 |
| Strand: | - |
| Coordinate: | | Start Site(bp): | 1086579 | End Site(bp): | 1095380 |
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| Gene Summary: | This gene encodes the fifth largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. This subunit is shared by the other two DNA-directed RNA polymerases and is present in two-fold molar excess over the other polymerase subunits. An interaction between this subunit and a hepatitis virus transactivating protein has been demonstrated, suggesting that interaction between transcriptional activators and the polymerase can occur through this subunit. A pseudogene is located on chromosome 11. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Oct 2015] |
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