ctcRbase

Entry Detail

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General Information

Database ID: BRCA02817 Cancer Type: breast cancer Dataset: GSE109761 CTCs/CTM Isolation Method: microfluidics immunofluorescence

Gene Information

ncRNA Symbol: DNAJB1 Full Name: DnaJ heat shock protein family (Hsp40) member B1 Category: mRNA Synonyms: HSPF1|Hdj1|Hsp40|RSPH16B|Sis1 Chromosome: chr19 Strand: - Coordinate: Start Site(bp): 14514770 End Site(bp): 14529770 Gene Summary: This gene encodes a member of the DnaJ or Hsp40 (heat shock protein 40 kD) family of proteins. DNAJ family members are characterized by a highly conserved amino acid stretch called the 'J-domain' and function as one of the two major classes of molecular chaperones involved in a wide range of cellular events, such as protein folding and oligomeric protein complex assembly. The encoded protein is a molecular chaperone that stimulates the ATPase activity of Hsp70 heat-shock proteins in order to promote protein folding and prevent misfolded protein aggregation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015] External Links: Ensembl ID: ENSG00000132002 HGNC ID: HGNC:5270 Entrez Gene: 3337

Expression Profile of DNAJB1 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-122-5p YES YES NO hsa-miR-128-3p YES YES YES hsa-miR-133a-3p YES YES YES hsa-miR-133b YES YES YES hsa-miR-137 YES YES YES hsa-miR-143-3p YES NO YES hsa-miR-155-5p YES YES YES hsa-miR-181a-5p YES YES YES hsa-miR-181b-5p YES YES YES hsa-miR-181c-5p YES YES YES hsa-miR-181d-5p YES YES YES hsa-miR-188-5p YES NO YES hsa-miR-193a-3p YES YES YES hsa-miR-193b-3p YES YES YES hsa-miR-19a-3p YES YES YES hsa-miR-19b-3p YES YES YES hsa-miR-204-5p YES YES YES hsa-miR-211-5p YES YES YES hsa-miR-219a-5p YES YES NO hsa-miR-296-5p YES NO YES hsa-miR-326 YES YES NO hsa-miR-328-3p YES YES NO hsa-miR-330-5p YES YES NO hsa-miR-340-5p YES YES YES hsa-miR-34a-5p YES YES YES hsa-miR-34c-5p YES YES YES hsa-miR-362-5p YES NO YES hsa-miR-370-3p YES YES YES hsa-miR-377-3p YES YES NO hsa-miR-378a-3p YES YES NO hsa-miR-383-5p YES YES YES hsa-miR-422a YES YES NO hsa-miR-449a YES YES YES hsa-miR-449b-5p YES YES YES hsa-miR-455-3p YES NO YES hsa-miR-486-5p YES NO YES hsa-miR-488-3p YES YES YES hsa-miR-543 YES YES YES hsa-miR-9-5p YES YES YES Display: