ctcRbase

Entry Detail

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General Information

Database ID: BRCA02849 Cancer Type: breast cancer Dataset: GSE41245 CTCs/CTM Isolation Method: CTC-Chip

Gene Information

ncRNA Symbol: MMACHC Full Name: metabolism of cobalamin associated C Category: mRNA Synonyms: cblC Chromosome: chr1 Strand: + Coordinate: Start Site(bp): 45500053 End Site(bp): 45513382 Gene Summary: The exact function of the protein encoded by this gene is not known, however, its C-terminal region shows similarity to TonB, a bacterial protein involved in energy transduction for cobalamin (vitamin B12) uptake. Hence, it is postulated that this protein may have a role in the binding and intracellular trafficking of cobalamin. Mutations in this gene are associated with methylmalonic aciduria and homocystinuria type cblC. [provided by RefSeq, Oct 2009] External Links: Ensembl ID: ENSG00000132763 HGNC ID: HGNC:24525 Entrez Gene: 25974

Expression Profile of MMACHC Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-let-7a-5p YES YES NO hsa-let-7b-5p YES YES NO hsa-let-7c-5p YES YES NO hsa-let-7d-5p YES YES NO hsa-let-7e-5p YES YES NO hsa-let-7f-5p YES YES NO hsa-let-7g-5p YES YES NO hsa-let-7i-5p YES YES NO hsa-miR-106a-5p YES YES NO hsa-miR-106b-5p YES YES NO hsa-miR-15a-5p YES YES NO hsa-miR-15b-5p YES YES NO hsa-miR-16-5p YES YES NO hsa-miR-17-5p YES YES NO hsa-miR-195-5p YES YES NO hsa-miR-20a-5p YES YES NO hsa-miR-20b-5p YES YES NO hsa-miR-22-3p YES YES YES hsa-miR-342-3p YES YES NO hsa-miR-424-5p YES YES NO hsa-miR-497-5p YES YES NO hsa-miR-519d-3p YES YES NO hsa-miR-93-5p YES YES NO hsa-miR-9-5p YES YES NO hsa-miR-98-5p YES YES NO Display: