| ncRNA Symbol: | XRCC6 |
| Full Name: | X-ray repair cross complementing 6 |
| Category: | mRNA |
| Synonyms: | CTC75|CTCBF|G22P1|KU70|ML8|TLAA |
| Chromosome: | chr22 |
| Strand: | + |
| Coordinate: | | Start Site(bp): | 41621119 | End Site(bp): | 41664048 |
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| Gene Summary: | The p70/p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single-stranded DNA-dependent ATP-dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double-strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with systemic lupus erythematosus. [provided by RefSeq, Jul 2008] |
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