ctcRbase

Entry Detail

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General Information

Database ID: BRCA02926 Cancer Type: breast cancer Dataset: GSE109761 CTCs/CTM Isolation Method: microfluidics immunofluorescence

Gene Information

ncRNA Symbol: HNRNPM Full Name: heterogeneous nuclear ribonucleoprotein M Category: mRNA Synonyms: CEAR|HNRNPM4|HNRPM|HNRPM4|HTGR1|NAGR1|hnRNP M Chromosome: chr19 Strand: + Coordinate: Start Site(bp): 8444767 End Site(bp): 8489114 Gene Summary: This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has three repeats of quasi-RRM domains that bind to RNAs. This protein also constitutes a monomer of the N-acetylglucosamine-specific receptor which is postulated to trigger selective recycling of immature GlcNAc-bearing thyroglobulin molecules. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2011] External Links: Ensembl ID: ENSG00000099783 HGNC ID: HGNC:5046 Entrez Gene: 4670

Expression Profile of HNRNPM Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-132-3p YES YES NO hsa-miR-212-3p YES YES NO hsa-miR-216a-5p YES YES NO hsa-miR-224-5p YES YES NO hsa-miR-300 YES YES NO hsa-miR-381-3p YES YES NO hsa-miR-421 YES YES NO hsa-miR-495-3p YES YES NO hsa-miR-505-3p YES YES YES hsa-miR-873-5p YES YES YES Display: