ctcRbase

Entry Detail

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General Information

Database ID: BRCA02929 Cancer Type: breast cancer Dataset: GSE67939 CTCs/CTM Isolation Method: Cluster-Chip

Gene Information

ncRNA Symbol: ARPC1B Full Name: actin related protein 2/3 complex subunit 1B Category: mRNA Synonyms: ARC41|PLTEID|p40-ARC|p41-ARC Chromosome: chr7 Strand: + Coordinate: Start Site(bp): 99374249 End Site(bp): 99394801 Gene Summary: This gene encodes one of seven subunits of the human Arp2/3 protein complex. This subunit is a member of the SOP2 family of proteins and is most similar to the protein encoded by gene ARPC1A. The similarity between these two proteins suggests that they both may function as p41 subunit of the human Arp2/3 complex that has been implicated in the control of actin polymerization in cells. It is possible that the p41 subunit is involved in assembling and maintaining the structure of the Arp2/3 complex. Multiple versions of the p41 subunit may adapt the functions of the complex to different cell types or developmental stages. This protein also has a role in centrosomal homeostasis by being an activator and substrate of the Aurora A kinase. [provided by RefSeq, Mar 2011] External Links: Ensembl ID: ENSG00000130429 HGNC ID: HGNC:704 Entrez Gene: 10095

Expression Profile of ARPC1B Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-124-3p YES YES YES hsa-miR-181a-5p YES YES NO hsa-miR-181b-5p YES YES NO hsa-miR-181c-5p YES YES NO hsa-miR-181d-5p YES YES NO hsa-miR-204-5p YES YES NO hsa-miR-211-5p YES YES NO hsa-miR-338-3p YES YES YES hsa-miR-33a-5p YES YES NO hsa-miR-33b-5p YES YES NO hsa-miR-433-3p YES NO YES hsa-miR-488-3p YES YES NO hsa-miR-494-3p YES YES NO hsa-miR-506-3p YES YES NO hsa-miR-543 YES YES NO Display: