ctcRbase

Entry Detail

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General Information

Database ID: BRCA02966 Cancer Type: breast cancer Dataset: GSE55807 CTCs/CTM Isolation Method: CTC-iChip

Gene Information

ncRNA Symbol: HSD17B4 Full Name: hydroxysteroid 17-beta dehydrogenase 4 Category: mRNA Synonyms: DBP|MFE-2|MPF-2|PRLTS1|SDR8C1 Chromosome: chr5 Strand: + Coordinate: Start Site(bp): 119452443 End Site(bp): 119637199 Gene Summary: The protein encoded by this gene is a bifunctional enzyme that is involved in the peroxisomal beta-oxidation pathway for fatty acids. It also acts as a catalyst for the formation of 3-ketoacyl-CoA intermediates from both straight-chain and 2-methyl-branched-chain fatty acids. Defects in this gene that affect the peroxisomal fatty acid beta-oxidation activity are a cause of D-bifunctional protein deficiency (DBPD). An apparent pseudogene of this gene is present on chromosome 8. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2014] External Links: Ensembl ID: ENSG00000133835 HGNC ID: HGNC:5213 Entrez Gene: 3295

Expression Profile of HSD17B4 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-21-5p YES YES NO hsa-miR-218-5p YES YES NO hsa-miR-411-5p YES YES NO hsa-miR-455-5p YES YES NO hsa-miR-494-3p YES YES NO hsa-miR-496 YES YES NO hsa-miR-590-5p YES YES NO Display: